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The term came into more common use after 1980. Bulgarian is the pdf proof approved translation lived longer lives because of this custom. 2001 defines probiotics as live micro-organisms that, “when administered in adequate amounts, confer a health benefit on the host.

In October 2001, this expert consultation defined probiotics as live micro-organisms that “when administered in adequate amounts, confer a health benefit on the host. This effort was accompanied by local governmental and supra-governmental regulatory bodies requirements to better characterize health claims substantiations. A group of scientific experts assembled in London, UK, on October 23, 2013, to discuss the scope and appropriate use of the term probiotic. The meeting was motivated by developments in the field since 2001.

The panel’s conclusions were published in June 2014. Probiotics must be alive when administered. One of the concerns throughout the scientific literature resides in the viability and reproducibility on a large scale of the observed results, as well as the viability and stability during use and storage, and finally the ability to survive in stomach acids and then in the intestinal ecosystem. Probiotics must have undergone controlled evaluation to document health benefits in the target host. Only products that contain live organisms shown in reproducible human studies to confer a health benefit can actually claim to be probiotic. The correct definition of health benefit, backed with solid scientific evidence, is a strong element for the proper identification and assessment of the effect of a probiotic.

It is commonly admitted that most effects of probiotics are strain-specific and cannot be extended to other probiotics of the same genus or species. This calls for a precise identification of the strain, i. Probiotics must be safe for their intended use. If the strain under evaluation belongs to a species that is a known mammalian toxin producer, it must be tested for toxin production. In Europe, EFSA has adopted a premarket system for safety assessment of microbial species used in food and feed productions, to set priorities for the need of risk assessment. Finally, probiotics must be supplied in adequate numbers, which may be defined as the number able to trigger the targeted effect on the host.

It depends on strain specificity, process, and matrix, as well as the targeted effect. 100 to 200 mg per day. Probiotics have received renewed attention in the 21st century from product manufacturers, research studies, and consumers. The history of probiotics can be traced to the first use of cheese and fermented products, that were well known to the Greeks and Romans who recommended their consumption.